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Research Associate II/Scientist, Downstream Process Development

Company: Bevov
Location: Spokane
Posted on: October 11, 2021

Job Description:

Job Description

Our client is a biotechnology company leading a new generation of gene therapy.  With their proprietary re-dosable ceDNA technology, they are expanding the reach of gene therapy. Our client's goal is to bring the life-saving benefits of gene therapy to more people, living with a broader range of diseases, in more places around the world. Their vision is to make the ravages of genetic disease as imaginary to the next generation as polio feels to children today.

They are a thriving, collaborative, creative community with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts.  

Our client seeks an enthusiastic and highly motivated Scientist to drive the development of downstream processes for the production of our novel gene therapy product. This position joins a team of scientists dedicated to developing downstream processes to support the manufacture of early-stage clinical material. The successful candidate will champion the continual improvement of our GMP compliant process to support several clinical drug substance candidates. Candidates with proven downstream process development experience and an ability to adapt to a dynamic environment will be highly valued. This role will have high visibility in a company that is expanding to support a dynamic pipeline.


  • Develop scalable and commercially viable processes for the purification of our novel genetic medicines. 
  • Support downstream activities both internally and externally to achieve key development milestones 
  • Author study plans, protocols, and reports. 
  • Design, prioritize and execute experiments including, operating range studies and process improvements. 
  • Manage and execute in-house lab work and studies supporting the development and generation of material for preclinical and clinical testing. 
  • Support scale-up of process steps including filtration (depth filtration, UFDF, sterile filtration), and chromatography (affinity, IEX, etc). 
  • Support downstream tech transfer to CMO and build strong relationships with collaborating companies. 
  • Prepare, analyze, and present data internally to cross-functional teams.


  • BS in Chemical Engineering, Biotechnology, or related discipline with minimum 6+ years of relevant experience or Master’s Degree with minimum of 4+ years of relevant experience.
  • Proven technical proficiency in downstream process development 
  • Ability to manage multiple projects and responsibilities simultaneously. 
  • Strong collaboration and team working skills 
  • Proven ability to work independently, effectively plan and analyze work activities and prioritize task completion to meet schedules and deadlines. 
  • Knowledge of cGMP, FDA, and USP guidelines practices is a plus.


Our client believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. They do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. They will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Keywords: Bevov, Spokane , Research Associate II/Scientist, Downstream Process Development, Other , Spokane, Washington

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